Biotransformación Fentanilo se metaboliza principalmente en el hígado mediante CYP3A4. | Biotransformation Fentanyl is metabolized primarily in the liver via CYP3A4. |
En el cuerpo metaboliza de forma activa por las enzimas hepáticas. | In the body metabolized to active form by liver enzymes. |
Cinacalcet se metaboliza en parte por la enzima CYP3A4. | Cinacalcet is metabolised in part by the enzyme CYP3A4. |
Biotransformación La deferiprona se metaboliza predominantemente a un conjugado glucurónido. | Biotransformation Deferiprone is metabolised predominantly to a glucuronide conjugate. |
Completamente soluble en agua y se obtiene metaboliza por completo. | Completely soluble in water and it gets entirely metabolized. |
Aliskiren se metaboliza marginalmente por los enzimas del citocromo P450. | Aliskiren is metabolised minimally by the cytochrome P450 enzymes. |
Se metaboliza aproximadamente el 1,4% de la dosis oral total. | Approximately 1.4% of the total oral dose is metabolised. |
Se metaboliza en el cuerpo como paracetamol (acetaminophen). | It is metabolised in the body as paracetamol (acetaminophen). |
Insuficiencia hepática Darunavir se metaboliza por el sistema hepático. | Hepatic impairment Darunavir is metabolised by the hepatic system. |
Tacrolimus también se metaboliza considerablemente en la pared intestinal. | Tacrolimus is also considerably metabolised in the intestinal wall. |
