nephritis

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Los resultados a largo plazo de la podocitopatía lúpica son relativamente buenos, pero podría ocurrir una transición a lesiones proliferativas (clases III y IV) (Chen D, Hu W. Lupus podocytopathy: a distinct entity of lupus nephritis J Nephrol.	The long-term outcomes of lupus podocytopathy are optimistic, but pathological transition could occur after renal relapses (Chen D, Hu W. Lupus podocytopathy: a distinct entity of lupus nephritis J Nephrol.
El receptor megalina, un miembro de la superfamilia de receptores LDL, se expresa en el extremo del proceso podocitario (donde se forman los complejos inmunes) (Ronco P, Debiec H. Molecular pathomechanisms of membranous nephropathy: from Heymann nephritis to alloimmunization.	The polyspecific receptor megalin, a member of the LDL-receptor superfamily, is expressed with clathrin at the sole of podocyte foot processes (where immune complexes are formed) (Ronco P, Debiec H. Molecular pathomechanisms of membranous nephropathy: from Heymann nephritis to alloimmunization.
Algunos pacientes presentan rash y hematuria (Batuman V, Meleg-Smith S. Nephritis, Interstitial.	Patients may present with rash and hematuria (Batuman V, Meleg-Smith S. Nephritis, Interstitial.
Otro mecanismo es lesión celular aguda causada por infección, viral o bacteriana, a menudo asociada con obstrucción o reflujo (Batuman V, Meleg-Smith S. Nephritis, Interstitial.	Another mechanism is acute cellular injury caused by infection, viral or bacterial, often associated with obstruction or reflux (Batuman V, Meleg-Smith S. Nephritis, Interstitial.
Aunque la presentación clínica es a menudo suficiente para hacer el diagnóstico, se requiere de la biopsia renal para el diagnóstico definitivo (Batuman V, Meleg-Smith S. Nephritis, Interstitial.	Although the clinical presentation is often sufficient to make the diagnosis, renal biopsy is required to make a definitive diagnosis (Batuman V, Meleg-Smith S. Nephritis, Interstitial.
La forma crónica se presenta con una gran variedad de causas, incluyendo enfermedades genéticas o metabólicas, uropatía obstructiva y exposición crónica a toxinas ambientales o ciertos medicamentos y hierbas (Tubulointerstitial nephritis, in: The Merck Manuak [Link]).	The chronic form occurs with a diverse array of causes, including genetic or metabolic disorders, obstructive uropathy, and chronic exposure to environmental toxins or to certain drugs and herbs (Tubulointerstitial nephritis, in: The Merck Manuak [Link]).